普通外科副主任,中美联合培养博士,暨南大学附属第一医院胃肠外科副主任医师,暨南大学附属第一医院临床引进人才,暨南大学全英医学教师,暨南大学优秀博士毕业生。2012年于广州中医药大学获得医学学士学位,2015年于暨南大学获得外科学硕士学位,2017-2018年获得国家公派留学基金于美国伊利诺伊大学芝加哥分校(University of Illinois at Chicago)进行博士联合培养,2019年获得暨南大学获得外科学博士学位。【学术任职】美国临床肿瘤学会(ASCO)会员、广东省医师协会胃肠外科分会委员、中国抗癌协会会员(CACA)。【主研方向】长期致力胃肠道疾病及胃肠道肿瘤的诊治于肿瘤免疫治疗,胃肠道肿瘤免疫微环境的机制研究、抗肿瘤血管生成、肿瘤靶向小分子药物、中医药天然药物靶向筛选的作用及机制研究。目前主持国家自然科学青年基金1项、省自然科学基金2项、广州市科技计划、中央高校基金各1项,以第二完成人获得广东医学科技三等奖,以第一或通讯作者在Gut、Matrix bioloyg、Cell Death Disease等权威SCI杂志发表论文40余篇,担任Cancer letters、cancer communications、journal of celluar and molecular medicine等多本SCI及国内核心期刊杂志审稿人。【获奖情况】2021年,靶向诱导肿瘤血管正常化及其机制研究,广东医学科技奖三等奖(第二完成人);2019年,暨南大学优秀博士毕业生;2017年,国家公派留学基金获得者;2014、2017、2018年暨南大学研究生国家奖学金;。【学术论著】1. Yang Y#,Chen Z#,Chu X#,Yan Q,He J,Guo Y,Zhao Z,Zhang Y,Hu D,Ding H,Zhao X,Pan Y,Dong H*,Wang L*,Pan J*. Targeting LAYN inhibits colorectal cancer metastasis and tumor-associated macrophage infiltration induced by hyaluronan oligosaccharides[J]. Matrix Biology,2023.DOI: https://doi.org/10.1016/j.matbio.2023.02.005,2. Li X#,Pan J#,Liu T#,Yin W,Miao Q,Zhao Z,Gao Y,Zheng W,Li H,Deng R,Huang D,Qiu S,Zhang Y,Qi Q,Deng L,Huang M,Tang P,Cao Y,Chen M*,Ye W*,Zhang D*. Novel TCF21high pericyte subpopulation promotes colorectal cancer metastasis by remodelling perivascular matrix. Gut. 2022,doi: 10.1136/gutjnl-2022-327913,3. Chen C#,Yang Y#,Guo Y#,He J,Chen Z,Qiu S,Zhang Y,Ding H*,Pan J*,Pan Y*. CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer[J]. Cell Death Dis,2023,14(4): 271.DOI: 10.1038/s41419-023-05803-2,4. Pan J#,Qiao Y#,Chen C#,Zang H,Zhang X,Qi F,Chang C,Yang F,Sun M,Lin S,Tang Q,Li L,Wang M,Wu M,Liu Y,Lai C*,Chen J*,Chen G*. USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1. Cell Death Dis. 2021; 12(11):1051.,5. Lin ZB#,Long P#,Zhao Z#,Zhang YR,Chu XD,Zhao XX,Ding H,Huan SW*,Pan YL*,Pan JH*. Long Noncoding RNA KCNQ1OT1 is a Prognostic Biomarker and mediates CD8(+) T cell exhaustion by regulating CD155 Expression in Colorectal Cancer[J]. Int J Biol Sci,2021,17(7): 1757-1768.,6. Pan J.#,Zhou H.,et al. 2019. LAYN is a prognostic biomarker and correlated with immune infiltrates in gastric and colon cancers. Frontiers in immunology,Jan 29;10:6. doi: 10.3389/fimmu.2019.00006 (ESI high citation),7. Pan J.#,Zhu S.,Huang J.,et al. Monitoring the Process of Endostar Induceing Tumor Vascular Normalization via Non-Contrast Intravoxel Incoherent Motion Diffusion-Weighted MRI.Frontiers in Oncology,Nov 13. https://doi.org/10.3389/fonc.2018.00524,8. Pan J.#,Zhou H.,Zhu S.,et al. 2018.Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer[J]. J Cell Physiol. Sep 7. doi: 10.1002/jcp.27228.,9. Pan J.#,Zhou H.,Zhao X.,et al. 2017. Long-Term Oncological Outcomes in Robotic Gastrectomy Versus Laparoscopic Gastrectomy for Gastric Cancer: A Meta-Analysis[J].Surg Endosc. Sep 29. doi: 10.1007/s00464-017-5891-4,10. Pan J.#,Zhou H.,Zhao X.,et al. 2017. Robotic thyroidectomy versus conventional open thyroidectomy for thyroid cancer: a systematic review and meta-analysis[J]. Surg Endosc,Mar 23. doi: 10.1007/s00464-017-5433-0.